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| MANUAL OF NAVAL PREVENTIVE MEDICINE
Etiologic agent
Incubation
Clinical syndrome
Confirmation
period
13. Vibrio chorerae
Isolation of toxigenic
a. 01 or 0139
1-5 days
Watery diarrhea, often
organism from stool or
accompanied by
vomitus or two or more ill
vomiting
persons
OR
Significant rise in
vibriocidal, bacterial-
agglutinating, or antitoxin
antibodies in acute- and
early convalescent-phase sera
among persons not recently
immunized
OR
Isolation of toxigenic
organism from epidemio-
ogically implicated food
b. non-01 and non-
1-5 days
Watery diarrhea
Isolation of organism of same
0139
serotype from stool of two or
more ill persons
4-30 hrs
Diarrhea
Isolation of kanagawa-
14. Vibrio
positive organism from stool
parahaemolyticus
of two or more ill persons
OR
Isolation of >105 kanagawa-
positive organisms/g from
epidemiologically implicated
food, provided specimen
properly handled
1-10 days,
Diarrhea, abdominal
Isolation of organism from
15. Yersinia
usually 4-
pain (often severe)
clinical specimen of two or
enterocolitica
6 days
more ill perons
OR
Isolation of pathogenic
strain or organism from
epidemiologically implicated
food
Chemical
1. Marine toxins
a. Ciguatoxin
1-48
Usually
Demonstration of ciguatoxin
hours,
gastrointestinal
in epidemiologically
usually 2-
symptoms followed by
implicated fish
8 hrs
neurologic symptoms
OR
(including parasthesia
Clinical syndrome among
of lips, tongue,
persons who have eaten a type
throat, or
of fish previously associated
extremities) and
with ciguatera fish poisoning
reversal of hot and
(e.g., snapper, grouper, or
cold sensation
barracuda)
138
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